Opioid rewards may depend on dopamine signals

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This reference is used to annotate "I would never send my kids to school" (2017) by Piotr Wozniak

[presented] data demonstrate that the rewarding and aversive effects of opioids are dependent on dopamine neural transmission within the mesolimbic system and suggest a role for the nucleus accumbens D-1 DA receptors in the mediation of both motivational effects

Title: Examination of the neurochemical substrates mediating the motivational effects of opioids: role of the mesolimbic dopamine system and D-1 vs. D-2 dopamine receptors

Authors: Shippenberg, Bals-Kubik R, Herz A

Link: https://www.ncbi.nlm.nih.gov/pubmed/8386244

Backlink: Biederman model