Opioid receptors form a gradient along a processing hierarchy

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This reference is used to support claims made by Dr Piotr Wozniak as part of an article series on memory, learning, creativity, and problem solving.

Stereospecific [3H]naloxone binding sites increased in a gradient along hierarchically organized cortical systems that sequentially process modality-specific sensory information of a progressively more complex nature. These results, in combination with electrophysiological studies of monkeys and humans, suggest that mu-like opiate receptors may play a role in the affective filtering of sensory stimuli at the cortical level, that is, in emotion-induced selective attention

Quoted excerpts come from the following reference:

Title: Opiate receptor gradients in monkey cerebral cortex: correspondence with sensory processing hierarchies

Backlink: Biederman model

Link: https://www.ncbi.nlm.nih.gov/pubmed/6258227